Pulmonary interstitial emphysema in newborns
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Updated: Sep 15, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Hortense Petat1, Juliette Raghani2, Isabelle Michelet3
1Paediatrics, CHU de Rouen, Rouen, France hortense.petat1@univ-rouen.fr.
Abstract:
Pulmonary interstitial emphysema (PIE) is a rare case of air leak syndrome in newborns, with air escaping from the tracheobronchial tree into the lung tissue.We observed 3 cases of PIE. The three newborns were moderately premature. The common initial presentation was respiratory distress, which subsequently worsened. The treatment was conservative, with positioning and oxygen therapy. Medium- and long-term outcomes were good, with patients remaining clinically symptom-free. However, follow-up CT scans revealed the persistence of sequelae bullae.Systematic medium- and long-term follow-up may be recommended to detect persistent respiratory symptoms and describe radiological evolution.
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