Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

222
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
222
Long-term Depression01:05

Long-term Depression

31.5K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
31.5K
Depression: Overview01:18

Depression: Overview

354
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
354
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

172
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
172
Uncertainty: Overview00:59

Uncertainty: Overview

988
In analytical chemistry, we often perform repetitive measurements to detect and minimize inaccuracies caused by both determinate and indeterminate errors. Despite the cares we take, the presence of random errors means that repeated measurements almost never have exactly the same magnitude. The collective difference between these measurements - observed values - and the estimated or expected value is called uncertainty. Uncertainty is conventionally written after the estimated or expected value.
988
Uncertainty: Confidence Intervals00:54

Uncertainty: Confidence Intervals

4.8K
The confidence interval is the range of values around the mean that contains the true mean. It is expressed as a probability percentage. The interpretation of a 95% confidence interval, for instance, is that the statistician is 95% confident that the true mean falls within the interval. The upper and lower limits of this range are known as confidence limits. The confidence limits for the true mean are estimated from the sample's mean, the standard deviation, and the statistical factor...
4.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Topotactic Leap: 2D Layers to 3D Large-Pore Zeolite.

Journal of the American Chemical Society·2026
Same author

Multi-objective Big Bang Big Crunch framework for reliable rice disease and variety classification with conditional calibration.

PloS one·2026
Same author

Explicable intensity-aware 3D cerebrovascular segmentation with planar representation.

Medical image analysis·2026
Same author

Comparative impacts of microplastics types on enrichment and transfer of antibiotic resistance genes in aquaculture: In situ evidence.

Marine pollution bulletin·2025
Same author

Uncovering the potential effect of microplastics on Alexandrium pacificum: From the perspective of cyst formation and toxin production.

Marine environmental research·2025
Same author

Single site of water-resistant asymmetric Bi-Ov-Mn for robust VOC ozonation at ambient temperature.

Chemical science·2025

Related Experiment Video

Updated: Sep 15, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.6K

Uncertainty aware domain incremental learning for cross domain depression detection.

Zita Lifelo1, Jianguo Ding2, Huansheng Ning1

  • 1School of Computer and Communications Engineering, University of Science and Technology Beijing, Beijing, 100083, China.

Scientific Reports
|July 14, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a novel framework for detecting Major Depressive Disorder (MDD) using text data, addressing privacy and data limitations in cross-domain settings. The method enhances depression detection accuracy by managing domain gaps and model uncertainty.

Keywords:
Class imbalanceData-free domain alignmentIncremental learningMajor depressive disorderUncertainty estimation

More Related Videos

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues
07:34

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues

Published on: June 3, 2013

17.5K
Cross-Modal Multivariate Pattern Analysis
13:51

Cross-Modal Multivariate Pattern Analysis

Published on: November 9, 2011

20.1K

Related Experiment Videos

Last Updated: Sep 15, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.6K
Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues
07:34

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues

Published on: June 3, 2013

17.5K
Cross-Modal Multivariate Pattern Analysis
13:51

Cross-Modal Multivariate Pattern Analysis

Published on: November 9, 2011

20.1K

Area of Science:

  • Computational psychiatry
  • Machine learning applications in mental health

Background:

  • Deep learning shows promise for Major Depressive Disorder (MDD) detection from text.
  • Existing methods struggle with limited data, privacy, domain gaps, and uncertainty in real-world applications.

Purpose of the Study:

  • To propose an Uncertainty-Aware Domain Incremental Learning framework for Cross-Domain Depression Detection (UDIL-DD).
  • To overcome challenges of data privacy, domain gaps, class imbalance, and uncertainty in depression detection.

Main Methods:

  • Developed Uncertainty-guided Adaptive Class Threshold Learning (UACTL) to measure prediction discrepancies and incorporate uncertainty.
  • Implemented Data-Free Domain Alignment (DFDA) to approximate historical feature distributions without accessing prior data, mitigating catastrophic forgetting.

Main Results:

  • The UDIL-DD framework demonstrated effectiveness in cross-domain depression detection.
  • Experiments on four benchmark datasets (CMDC, DIAC-WoZ, MODMA, EATD) validated the method's robustness.

Conclusions:

  • The proposed UDIL-DD framework offers a reliable approach for depression detection in real-world clinical scenarios.
  • The integration of UACTL and DFDA effectively handles data privacy and domain shift challenges.