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Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia
Published on: April 7, 2023
Research status and hotspots in the field of hyperlipidemia and metabolism: A bibliometric study
1Geriatric Services and Management Department, Changsha Social Work College, Changsha, China.
Purpose:
This study aims to discuss the status and developmental trends in the research related to hyperlipidemia (HLP) and metabolism.
Methods:
The literature related to HLP and metabolism from 2011 to 2022 was searched and analyzed using CiteSpace.
Results:
A total of 5490 papers were retrieved, with a steady increase in the number of publications annually. While 624 authors have contributed to relevant literature, there is a lack of a large-scale collaborative author network. China is the country with the largest number of publications, with a total of 1610 papers published. Research in this field primarily focuses on the mechanism of insulin resistance, metabolic syndrome, intestinal flora, and treatment of HLP. Nonalcoholic fatty liver disease, fibrosis, intestinal flora, and metabonomics were identified as key research frontiers in this field.
Conclusion:
Cooperation among authors, institutions, and countries in this field is currently decentralized, highlighting the importance of strengthening exchanges, and cooperation for high-quality research. Intestinal flora and metabolomics are projected to be the key research direction in the field.
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