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Are Your Kidneys Ok? Detect Early to Protect Kidney Health
Joseph A Vassalotti1, Anna Francis2, Augusto Cesar Soares Dos Santos3
1Mount Sinai Hospital, Department of Medicine-Renal Medicine, New York, New York, USA; National Kidney Foundation, Inc., New York, NY, USA.
American Journal of Hypertension
|July 15, 2025
Summary
Early detection of kidney disease through simple tests like serum creatinine and urine albumin can prevent complications and reduce mortality. Screening high-risk populations is crucial for global kidney health, especially with new treatments available.
Area of Science:
- Nephrology
- Public Health
Background:
- Early identification of kidney disease is vital for preserving kidney health and preventing severe complications.
- Chronic kidney disease (CKD) often presents asymptomatically in early stages, necessitating proactive screening.
- New treatments, such as sodium-glucose co-transporter-2 inhibitors, improve outcomes and support the rationale for early detection programs.
Purpose of the Study:
- To emphasize the importance of early kidney disease identification and screening.
- To advocate for case-finding in high-risk populations and population-level screening strategies.
- To highlight the benefits of early detection in reducing the global burden of kidney disease.
Main Methods:
- Utilizing serum creatinine to estimate kidney function.
- Employing urine albumin tests to assess kidney and endothelial damage.
- Evaluating risk factors including diabetes, blood pressure, and body mass index.
Main Results:
- Early detection protects kidney health, prevents disease progression, and reduces cardiovascular risk and mortality.
- Screening high-risk groups can significantly decrease the global impact of kidney disease.
- New therapeutic advancements enhance the cost-benefit analysis for screening initiatives.
Conclusions:
- Proactive screening and case-finding are essential for managing and reducing the global burden of kidney disease.
- Addressing barriers like resource allocation and awareness is critical for successful implementation of screening programs.
- Coordinated efforts and integration with existing health programs can maximize the efficiency of early kidney disease detection.
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