Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

29
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
29
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

25
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
25
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

47
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
47
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

59
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
59
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

42
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
42
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

46
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
46

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Kinematic-calcium loops unravel impaired excitation-contraction coupling in MELAS-affected cardioids.

The Journal of physiology·2026
Same author

Ileal Bile Acid Transporter Inhibitors for Symptomatic Cholestasis due to Vanishing Bile Duct Syndrome in Adults.

ACG case reports journal·2026
Same author

Fully percutaneous emergency management of an acute myocardial infarction complicated by papillary muscle rupture treated with percutaneous revascularization and mitral transcatheter edge-to-edge repair: a case report.

European heart journal. Case reports·2026
Same author

Pitfalls in Echocardiography: Superior Aortic Recess Pericardial Effusion Mimicking Ascending Aorta Dissection.

Journal of cardiovascular echography·2026
Same author

Clinical relevance and prognostic role of PDL-1 expression in cervical cancer patients.

Archives of gynecology and obstetrics·2026
Same author

Next-generation sequencing methodologies to identify patients for targeted therapy: focus on HR+/HER2- metastatic breast cancer.

Pathologica·2026

Related Experiment Video

Updated: Sep 15, 2025

A New Murine Model of Endovascular Aortic Aneurysm Repair
08:51

A New Murine Model of Endovascular Aortic Aneurysm Repair

Published on: July 7, 2013

14.5K

Recurrent Systemic Embolization in a Patient With Aortic Valve Amyloidosis.

Annalisa Caputo1, Amedeo Pergolini2, Luigi Monticelli3

  • 1Department of Cardiovascular and Respiratory Science, Sapienza University of Rome, Rome, Italy.

Echocardiography (Mount Kisco, N.Y.)
|July 15, 2025
PubMed
Summary
This summary is machine-generated.

A rare case highlights aortic valve thrombosis due to isolated aortic valve amyloidosis in a patient with antiphospholipid syndrome. This rare condition led to recurrent thromboembolic events, including STEMI and limb ischemia.

Keywords:
amylodosisaortic valveechocardiographyy

More Related Videos

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
07:21

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice

Published on: September 28, 2015

38.0K
Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.2K

Related Experiment Videos

Last Updated: Sep 15, 2025

A New Murine Model of Endovascular Aortic Aneurysm Repair
08:51

A New Murine Model of Endovascular Aortic Aneurysm Repair

Published on: July 7, 2013

14.5K
Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
07:21

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice

Published on: September 28, 2015

38.0K
Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.2K

Area of Science:

  • Cardiology
  • Hematology
  • Pathology

Background:

  • Antiphospholipid syndrome (APS) is an autoimmune disorder associated with an increased risk of thrombosis.
  • Aortic valve amyloidosis is a rare condition characterized by the deposition of amyloid protein in the aortic valve.

Observation:

  • A 47-year-old woman presented with recurrent thromboembolic events, including ST-elevation myocardial infarction (STEMI) and lower limb ischemia.
  • Diagnostic workup revealed aortic valve thrombosis.

Findings:

  • The aortic valve thrombosis was attributed to isolated aortic valve amyloidosis.
  • The patient had overlapping antiphospholipid syndrome, complicating the clinical picture.

Implications:

  • This case underscores the importance of considering rare causes of aortic valve thrombosis in patients with recurrent thromboembolic events and APS.
  • Early diagnosis and management are crucial to prevent severe cardiovascular complications.