Locally advanced port-site metastasis following laparoscopic surgery for early-stage endometrial carcinoma: a case...

Port-site metastasis (PSM) following minimally invasive surgery for early-stage endometrial cancer is rare, and its underlying pathophysiology remains poorly understood. Currently, no standardized treatment protocol exists. We report the case of a 66-year-old woman who developed a locally advanced PSM 18 months after undergoing laparoscopic surgery for early-stage endometrioid adenocarcinoma. She was treated with neoadjuvant chemotherapy to reduce the mass and enable complete surgical resection. Although the incidence of PSM is low, its management poses significant clinical challenges and can be associated with a poor prognosis. Early recognition, an adapted multidisciplinary approach, and implementation of preventive strategies during initial surgery are critical to optimizing outcomes.