The Evolving Field of Cardio-Rheumatology: Global Patterns and Research Gaps, 1953-2025

Olatokun Akano1,2, Oluwaremilekun Tolu-Akinnawo3, Kelechukwu P Ughagwu4

  • 1Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, USA.

Cureus
|July 15, 2025
PubMed

Insights

Cardio-rheumatology research is growing rapidly, with the US leading. However, limited international collaboration hinders progress in understanding cardiovascular complications in autoimmune diseases.

Area of Science:

  • Cardio-rheumatology
  • Intersection of cardiovascular and autoimmune diseases
  • Bibliometric analysis

Background:

  • Increasing clinical and research interest in cardio-rheumatology.
  • Rising burden of cardiovascular complications in rheumatic conditions.
  • Intellectually fragmented nature of the field.

Purpose of the Study:

  • To assess publication trends, citation metrics, authorship patterns, and global contributions in cardio-rheumatology.
  • To identify dominant and emerging themes within the field.
  • To highlight the need for interdisciplinary and international integration.

Main Methods:

  • Bibliometric analysis of 3,709 articles.
  • Data sourced from Scopus databases.
  • Analysis period: 1953 to March 2025.

Main Results:

  • Sharp increase in cardio-rheumatology publications post 2010.
  • United States leads in publication volume and impact.
  • Limited international collaboration (11.6% multi-country authorship).
  • Concentrated productivity among a few contributors.
  • Dominant themes: myocarditis, pericarditis, accelerated atherosclerosis.
  • Emerging areas: cardiac sarcoidosis, advanced imaging, biologic therapy-associated cardiotoxicity.

Conclusions:

  • Cardio-rheumatology is a rapidly evolving field with significant growth.
  • Greater interdisciplinary and international collaboration is essential.
  • Advancing the field requires integrated efforts to improve patient outcomes.

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