Minimum Continuous Glucose Monitor Data Required to Assess Glycemic Control in Youth with Type 1 Diabetes

Area of Science:

• Endocrinology
• Metabolic Diseases
• Pediatric Diabetes Management

Background:

• Continuous Glucose Monitoring (CGM) is crucial for managing type 1 diabetes (T1D).
• Current guidelines recommend 14 days of CGM data for glycemic assessment in T1D.
• Adult studies suggest 7 days of CGM data may be sufficient.

Purpose of the Study:

• To determine the minimum duration of CGM data needed for reliable glycemic assessment in pediatric T1D.
• To evaluate the correlation between shorter CGM data windows and established 14-day metrics.
• To identify factors influencing the required CGM data duration in youth.

Main Methods:

• Real-world Dexcom G6 CGM data from 1316 youth with T1D were analyzed.
• Data from 8 time windows (3-90 days) were compared to 14-day metrics.
• Statistical analyses included Pearson correlation, ICCs, and chi-squared tests.

Main Results:

• Pearson correlation and ICCs between 14-day and other windows exceeded 0.9 for GMI and TIR.
• Categorical agreement for GMI and TIR thresholds reached >90% at 10 days.
• Agreement was stronger for youth with Time in Range (TIR) ≥70% and Coefficient of Variation (CV) <36%.

Conclusions:

• Approximately 9.6 days of CGM data provide a reliable glycemic assessment in pediatric T1D.
• For youth with higher TIR and lower CV, 7 days of CGM data may be adequate.
• This research refines data requirements for pediatric T1D management using CGM.