Related Experiment Video
Updated: Sep 15, 2025
Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
Published on: November 7, 2020
Oral Manifestations in the Post COVID-19 Condition: A Systematic Review With Meta-Analysis.
Letícia Simeoni Avais1,2, Elis Carolina Pacheco2, Luisa Pereira de Oliveira Zanetti Gomes3
1Department of Microbiology and Immunology, Georgetown University School of Medicine, Washington, District of Columbia, USA.
Post-COVID-19 condition, or Long COVID, frequently causes oral symptoms like taste loss. This review found taste dysfunction in 8% of patients beyond 12 weeks, highlighting the need for oral health professional awareness.
Area of Science:
- Oral Medicine
- Infectious Diseases
- Systematic Reviews
Background:
- Post-COVID-19 condition (Long COVID) presents diverse persistent symptoms.
- Oral manifestations, including taste loss and dry mouth, are recognized Long COVID symptoms.
- Understanding the prevalence and characteristics of these oral symptoms is crucial for patient management.
Purpose of the Study:
- To systematically review and report the frequency and characteristics of oral symptoms in adults with Post-COVID-19 condition.
- To estimate the prevalence of taste dysfunction and other oral manifestations using meta-analysis.
Main Methods:
- Systematic review adhering to PROSPERO and PRISMA guidelines.
- Included observational studies on COVID-19-positive adults with post-COVID oral symptoms.
- Searched six databases (Medline/PubMed, Embase, Web of Science, Cochrane, SCOPUS, LILACS) in January 2024.
- Assessed risk of bias (Joanna Briggs Institute) and certainty of evidence (GRADE).
- Conducted meta-analysis using the inverse variance method for prevalence estimation.
Main Results:
- 107 observational studies involving 4552 articles were included.
- Taste dysfunction persisted in 8% (95% CI 6%-10%) of patients beyond 12 weeks post-infection.
- Combined taste and smell alterations affected 17% (95% CI 13%-21%) of patients.
- Less frequent symptoms included hyposalivation, periodontitis, mouth ulcers, tongue changes, facial tingling, trigeminal nerve sensitivity, dysphagia, and hard palate lesions.
Conclusions:
- Taste alterations are the most prevalent oral symptom in Post-COVID-19 condition.
- Clinical recognition and management by oral health professionals are essential.
- Further research is necessary to elucidate the prevalence, mechanisms, and clinical implications of diverse oral manifestations in Long COVID.
More Related Videos
08:05Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
06:29Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
Published on: May 25, 2022
Related Concept Videos
01:20COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
01:29Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
01:24Asthma-III: Symptoms and Complications
Classification of Asthma
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation