The NeVa Net stent-retriever - initial report of 20 cases from two high volume centres

Area of Science:

• Interventional Neurology
• Medical Device Technology
• Cerebrovascular Disease Management

Background:

• Mechanical thrombectomy is crucial for acute ischemic stroke treatment, with first-pass recanalization significantly impacting patient outcomes.
• Novel stent-retrievers aim to improve procedural efficiency and reduce complications like distal embolization.

Purpose of the Study:

• To evaluate the initial clinical experience and safety of the NeVa NET stent-retriever, a new device featuring an integrated distal microfiltration net.
• To assess the efficacy of the NeVa NET in achieving first-pass recanalization and preventing embolic complications in stroke patients.

Main Methods:

• A retrospective review of prospectively maintained databases identified 20 patients treated with the NeVa NET 4x30mm device.
• Data collected included baseline demographics, stroke severity (NIHSS, ASPECT), clot characteristics, procedural outcomes (eTICI scores), complications, and 90-day modified Rankin Scale (mRS) scores.

Main Results:

• The NeVa NET was successfully tracked in 18 out of 20 patients.
• A high first-pass recanalization rate (eTICI ≥ 2c) of 94% was observed, with a final recanalization rate of 94%.
• No new emboli to distal territories, vessel ruptures, or dissections were reported. 50% of patients achieved a favorable outcome (mRS 0-2).

Conclusions:

• The NeVa NET stent-retriever, with its unique design for preventing distal embolization, demonstrated a very high rate of first-pass and final successful recanalization in this initial patient cohort.
• This novel technology shows potential for improving mechanical thrombectomy outcomes, and further investigation in larger studies is warranted.