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Updated: Sep 8, 2025
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Facile High-Throughput Pre-purification of Biological Samples for Library-Scale Peptide Interaction Studies
Ulrike Beutling1, Sven-Kevin Hotop1, Ronald Frank2
1Department of Chemical Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
None:
Peptides and peptide libraries are valuable probes in solid-phase binding assays and widely used in studies of protein-protein interactions. However, a high unspecific background can disturb or even inhibit a successful experiment. We describe an easy and flexible method for pre-purification of samples that is particularly well-suited for high-throughput processing of large numbers of samples.
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