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Stationary Cycling Exercise With Virtual Reality to Reduce Depressive Symptoms Among People With Mild to Moderate
Na Zhang1,2, Chenlu Hong3, Yuejia Wang1
1Huzhou Third Municipal Hospital, No. 2088 Tiaoxiao East Road, Wuxing District, Huzhou City, Zhejiang Province, Huzhou, Zhejiang, 313000, China, 86 13757289010.
Journal of Medical Internet Research
|July 15, 2025
Summary
Virtual reality (VR) stationary cycling significantly reduced depressive symptoms in adults with mild to moderate depression. This VR intervention shows promise for clinical practice and improved adherence to exercise for depression management.
Area of Science:
- Mental Health
- Exercise Science
- Digital Health
Background:
- Depression is a prevalent mental health condition often associated with low adherence to traditional treatments.
- Virtual reality (VR) stationary cycling presents a novel approach to potentially improve adherence and reduce depressive symptoms.
- High-quality evidence is required to integrate VR interventions into clinical practice for depression.
Purpose of the Study:
- To evaluate the clinical effects of a 12-week VR-based stationary cycling program on depressive symptoms.
- To assess the impact on sedentary adults diagnosed with mild to moderate depression.
Main Methods:
- A 12-week, 3-arm randomized controlled double-blind trial involving 114 participants (aged 18-60) with depression.
- Participants were assigned to VR high-intensity cycling, VR moderate-intensity cycling, or non-VR moderate-intensity cycling.
- The primary outcome was the change in depressive symptoms measured by the Hamilton Depression Rating Scale (HAMD-17) from baseline to 12 weeks.
Main Results:
- All groups demonstrated significant improvements in depressive symptoms.
- VR-based groups exhibited greater symptom reduction compared to the non-VR group (mean difference: 3.3-3.9).
- VR moderate-intensity cycling reported higher participant satisfaction, though symptom improvement was similar between VR groups.
Conclusions:
- VR stationary cycling is an effective intervention for alleviating depressive symptoms in individuals with mild to moderate depression.
- Findings support the integration of VR interventions into clinical practice for depression.
- VR cycling may enhance adherence and serve as a complementary treatment for depression.
Keywords:
adherencecyclingdepressive symptomsexercise therapyrandomized controlled trialvirtual reality
