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Updated: Sep 15, 2025

Author Spotlight: Unraveling the Interplay Between Trichoderma stromaticum and the Mammalian Immune System
Published on: October 20, 2023
Exploring the multifaceted roles of Trichoderma secondary metabolites
Kavita Yadav1, Prashant Khare1
1Xenesis, Absolute, 5th floor, Plot 68, Sector-44, Gurugram 122003, Haryana, India.
Abstract:
The genus Trichoderma comprises many common fungi species that are distributed across the ecosystems. Trichoderma species have been successfully used as biofungicides due to their ability to protect plants and produce secondary metabolites (SMs) such as peptaibols, butenolides, pyridines, koninginins, and polyketide compounds. These SMs possess antimicrobial properties that allow the microbe to suppress or eliminate other pathogens, enabling it to secure a competitive nutritional niche. These SMs function as key agents in biocontrol strategies, contributing to crop protection and plant growth promotion, and are increasingly utilized in the development of bio-fertilizers. Trichoderma functions through multiple mechanisms that support plant health by inducing systemic resistance and by activating plant defense pathways. This article aims to review the bioactivity of selected Trichoderma-derived SMs with an emphasis on their beneficial effects, growth promoting attributes, and their effects on fungal prey. Additionally, the article provides a comprehensive overview of SMs in promoting sustainable agriculture and biological control.
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