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Related Concept Videos

Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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Tumor Progression02:07

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Adaptive Mechanisms in Cancer Cells02:53

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Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
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Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
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Processing Speed in Patients with Cancer: A Concept Analysis.

Myeong-Ga Cho1, Catherine M Bender1

  • 1University of Pittsburgh School of Nursing, Pennsylvania.

Seminars in Oncology Nursing
|July 15, 2025
PubMed
Summary

Processing speed, crucial for cognitive aging, declines in cancer patients. Clarifying its attributes, antecedents, and consequences aids in developing targeted nursing interventions for improved cognitive function in cancer care.

Keywords:
Cancer survivorsCognitionCognitive dysfunctionProcessing speedPsycho-oncologyPsychomotor performance

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Area of Science:

  • Cognitive Science
  • Oncology Nursing
  • Neuroscience

Background:

  • Processing speed is a key cognitive domain and predictor of cognitive aging.
  • It often declines in cancer patients, impacting attention, executive function, and memory.
  • Lack of conceptual clarity hinders precise assessments and effective nursing interventions.

Purpose of the Study:

  • To analyze and clarify the concept of processing speed.
  • To define its attributes, antecedents, and consequences within the cancer context.
  • To inform the development of refined assessment tools and nursing interventions.

Main Methods:

  • Walker and Avant's concept analysis method was employed.
  • Literature search conducted across PubMed, CINAHL, and APAPsycINFO databases.

Main Results:

  • Defining attributes include sensory recognition, decision-making, and motor implementation speed.
  • Antecedents encompass aging, brain connectivity, fine motor function, cancer, and cancer treatment.
  • Consequences primarily involve overall cognitive capability.

Conclusions:

  • Clarifying processing speed enhances assessment tools and nursing interventions for cancer patients.
  • Refined clinical nursing practices are needed to evaluate and improve processing speed.
  • Targeted interventions can address cancer-related cognitive decline and improve patient health outcomes.