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Updated: Sep 15, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
A multidisciplinary approach to eosinophilic esophagitis presenting with feeding dysfunction
Emily Sitner-Medvedovsky1, Nina Gabriella Sparacio1, Bibiana Bernal1
1Department of Pediatrics, New York Presbyterian Brooklyn Methodist Hospital, 506 6th Street, Brooklyn, NY 11215, New York.
Eosinophilic Esophagitis (EoE) is a chronic immune disorder causing esophageal issues. This case highlights EoE diagnosis in a 12-month-old infant presenting with feeding intolerance.
Area of Science:
- Gastroenterology
- Immunology
- Pediatrics
Background:
- Eosinophilic Esophagitis (EoE) is a chronic, immune-mediated esophageal disorder.
- It causes varied symptoms from infancy to childhood, including feeding difficulties and dysphagia.
- Management requires a multidisciplinary approach with steroids, diet, and pharmacotherapies.
Observation:
- A previously healthy 12-month-old female presented with a 3-week illness.
- The infant showed acute feeding intolerance and hypersensitivity reactions.
- These symptoms led to a diagnosis of EoE.
Findings:
- The case illustrates a pediatric presentation of Eosinophilic Esophagitis.
- Diagnostic challenges in infants with EoE are highlighted.
- The patient's symptoms were consistent with esophageal dysfunction.
Implications:
- Early diagnosis of EoE in infants is crucial for effective management.
- This case underscores the importance of recognizing diverse EoE presentations.
- Understanding EoE pathophysiology aids in developing targeted therapies.
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