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Related Experiment Video

Updated: Sep 15, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

A multidisciplinary approach to eosinophilic esophagitis presenting with feeding dysfunction.

Emily Sitner-Medvedovsky¹, Nina Gabriella Sparacio¹, Bibiana Bernal¹

¹Department of Pediatrics, New York Presbyterian Brooklyn Methodist Hospital, 506 6th Street, Brooklyn, NY 11215, New York.

Oxford Medical Case Reports

|July 16, 2025

Summary

Eosinophilic Esophagitis (EoE) is a chronic immune disorder causing esophageal issues. This case highlights EoE diagnosis in a 12-month-old infant presenting with feeding intolerance.

Keywords:

EoE elemental diet eosinophilic esophagitis feeding difficulties food hypersensitivity multidisciplinary health team topical steroids

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Last Updated: Sep 15, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

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Area of Science:

Gastroenterology
Immunology
Pediatrics

Background:

Eosinophilic Esophagitis (EoE) is a chronic, immune-mediated esophageal disorder.
It causes varied symptoms from infancy to childhood, including feeding difficulties and dysphagia.
Management requires a multidisciplinary approach with steroids, diet, and pharmacotherapies.

Observation:

A previously healthy 12-month-old female presented with a 3-week illness.
The infant showed acute feeding intolerance and hypersensitivity reactions.
These symptoms led to a diagnosis of EoE.

Findings:

The case illustrates a pediatric presentation of Eosinophilic Esophagitis.
Diagnostic challenges in infants with EoE are highlighted.
The patient's symptoms were consistent with esophageal dysfunction.

Implications:

Early diagnosis of EoE in infants is crucial for effective management.
This case underscores the importance of recognizing diverse EoE presentations.
Understanding EoE pathophysiology aids in developing targeted therapies.