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Apple Cider Vinegar-Induced Hepatotoxicity: A Rare Case Report
Celina R Andonie1, Saja I AbuGhannam1, Shadi M A Ruzayqat2
1Faculty of Medicine, Al Quds University, University Street, Abu Dis, Jerusalem, P.O. Box 89, Postal Code P144, Palestine.
Oxford Medical Case Reports
|July 16, 2025
Summary
Apple cider vinegar can cause liver damage, though it is rare. A case study showed a man recovered after stopping long-term consumption, highlighting the need to consider vinegar as a potential cause of hepatotoxicity.
Area of Science:
- Gastroenterology and Hepatology
- Toxicology
Background:
- Apple cider vinegar (ACV) is a widely used culinary ingredient with a long history of consumption.
- While generally considered safe, reports of ACV-induced liver damage are uncommon in medical literature.
Observation:
- A 60-year-old male patient presented with hepatotoxicity.
- The patient had a significant history of long-term apple cider vinegar consumption.
Findings:
- The case study identified apple cider vinegar as the likely cause of the patient's liver damage (hepatotoxicity).
- The patient's liver function improved significantly after discontinuing ACV intake.
Implications:
- This case underscores the importance of considering even common dietary substances, such as apple cider vinegar, as potential etiological factors in drug-induced liver injury.
- Further investigation into the mechanisms of ACV-induced hepatotoxicity may be warranted.
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