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Updated: Sep 15, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Design, Synthesis, and Biological Evaluation of Novel Hydroxyamidine Derivatives as Indoleamine 2,3-Dioxygenase 1

Xiaodan Qiu1, Yitong Liu1, Xia Zhou1,2

  • 1Institute of Medicinal Biotechnology, Peking Union Medical College & Chinese Academy of Medical Sciences, Tian Tan Xi Li No.1, Beijing 100050, PR China.

ACS Medicinal Chemistry Letters
|July 16, 2025
PubMed

Keywords:
IDO1hydroxyamidine derivativestumor immunotherapy

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