Related Experiment Video
Updated: Sep 15, 2025

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
Published on: February 1, 2016
SymPET, a waveform digitizing "System on Chip" for ultra-high resolution TOF PET: design concept and preliminary
K Flood1, C Chock1, L Blackberg2
1Nalu Scientific LLC, Honolulu, HI, USA.
SymPET, a novel microchip for Positron Emission Tomography (PET), achieves sub-10 picosecond timing jitter. This breakthrough enables higher resolution brain imaging with improved power efficiency.
Area of Science:
- Medical Physics
- Instrumentation
- Nuclear Engineering
Background:
- Positron Emission Tomography (PET) systems require advanced readout electronics for high-resolution imaging.
- Current technologies face limitations in timing precision, channel density, and power consumption.
- Silicon Photomultiplier (SiPM) detectors are crucial for Time-of-Flight (TOF) PET applications.
Purpose of the Study:
- To develop SymPET, a low-power, high channel density, waveform-digitizing readout microchip.
- To improve timing precision and enable advanced features for SiPM-based TOF PET.
- To address challenges in heat dissipation for high-resolution PET designs.
Main Methods:
- Development of a "System on Chip" (SoC) architecture for waveform digitization.
- Integration of features like random accessible analog storage, input triggering, and on-chip biasing.
- Implementation of waveform feature extraction for optimizing system parameters.
- Focus on controlling systematic effects impacting timing precision.
Main Results:
- SymPET demonstrates less than 10 picoseconds (ps) timing jitter.
- Achieves this performance within a reasonable power budget.
- Offers substantial improvement over existing readout solutions.
- Enables optimization of throughput, speed, and buffer length.
Conclusions:
- SymPET provides superior timing jitter performance for TOF PET applications.
- Facilitates high-channel density and limited-angle PET designs, such as ultra-high resolution brain scanners.
- Addresses critical heat dissipation management for advanced PET systems requiring high spatial and timing resolution.
More Related Videos
10:21Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
Published on: August 8, 2019
11:09High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022