A Case Report of an Unusual Presentation of Plexiform Epithelioid Schwannoma

Plexiform epithelioid schwannoma (PES) is a rare, benign nerve sheath tumor that can resemble malignant tumors, making diagnosis challenging. We present the case of a 46-year-old Filipino man with a slow-growing mass on his chin. After surgical excision, histopathology confirmed it as PES. Immunohistochemistry supported the diagnosis, showing strong S-100 and SOX10 positivity. The patient recovered well, with no signs of local recurrence. This case highlights the importance of thorough pathological evaluation when diagnosing rare tumors like PES.