Balo Concentric Sclerosis: A Rare Variant of Multiple Sclerosis With Excellent Response to Early Steroid Treatment

Balo concentric sclerosis (BCS) is a rare and aggressive variant of multiple sclerosis (MS), characterized by unique alternating concentric layers of demyelinated and preserved myelin on neuroimaging. We present a case of a 34-year-old male patient with progressive right-sided weakness, whose MRI brain findings confirmed BCS. The patient demonstrated rapid clinical improvement with early initiation of high-dose corticosteroids. The Expanded Disability Status Scale (EDSS) score improved from 6 to 1 within one month, underscoring the importance of timely intervention. Early recognition and prompt treatment are critical to improving outcomes in BCS, as delays can lead to irreversible neurological damage. This case highlights the significant role of early high-dose corticosteroid therapy in achieving clinical improvement and preventing long-term disability.