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Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

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Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
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Ultrasonography01:17

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Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
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Related Experiment Video

Updated: Sep 15, 2025

Focused Ultrasound Induced Blood-Brain Barrier Opening for Targeting Brain Structures and Evaluating Chemogenetic Neuromodulation
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Breaking Barriers With Sound: Focused Ultrasound in the Brain.

Tejas Padliya

    IEEE Pulse
    |July 16, 2025
    PubMed
    Summary

    Focused ultrasound (FUS) offers noninvasive brain therapy with MRI guidance for precise treatment. This technology shows promise for essential tremor, Parkinson's disease, and investigational uses like Alzheimer's and drug delivery.

    Area of Science:

    • Neurosurgery
    • Medical Imaging
    • Biotechnology

    Background:

    • Focused ultrasound (FUS) presents a noninvasive alternative to traditional neurosurgery.
    • Advances in technology enable precise targeting through the skull.

    Purpose of the Study:

    • To provide an overview of FUS technologies and applications.
    • To highlight FUS's potential in treating neurological disorders and drug delivery.

    Main Methods:

    • Utilizes phased-array transducer technology for focused energy delivery.
    • Employs MRI-guided targeting, thermometry, and real-time imaging for safety.
    • Incorporates phase correction for skull variability.

    Main Results:

    • Achieved sub-millimeter accuracy in targeting brain tissue.

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  • Demonstrated durable tremor control and motor improvement in clinical trials.
  • Showcased ability for noninvasive drug delivery and targeting deep brain circuits.

    • Conclusions:

    • FUS technology is revolutionizing brain therapy with high precision and safety.
    • Broadening clinical applications include FDA-approved treatments and investigational therapies for various neurological conditions.