Related Experiment Video
Updated: Sep 15, 2025
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Association between removable denture-wearing and systemic diseases: A scoping review
Tong Wah Lim1, Karuna Julia Ka Wing Li1, Jingyu Wang1
1Division of Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR.
Objective:
This scoping review aimed to assess and summarize the existing evidence from clinical studies regarding the association between removable denture-wearing and systemic diseases, while elucidating the potential mechanisms underlying this relationship.
Data, Sources, And Study Selection:
An electronic search was conducted on five databases, including PubMed, Embase, Web of Science, Scopus and CINAHL Plus and one register Cochrane, for articles published in the English language. From the initial search, 11,681 articles were identified. After removal of duplicates, there were 5,107 articles. Forty-five full-text studies were assessed for eligibility. After excluding studies that did not meet the eligibility criteria, a total of 30 studies were included in the final scoping review and additional studies were included in the discussion of this review to support evidence. Data were extracted and summarized in tabular form.
Conclusions:
Five categories of systemic diseases have been found to be clinically and meaningfully associated with the removable denture-wearing. The existing clinical studies suggested a potential positive association between removable denture-wearing and respiratory diseases. Other systemic diseases, including cardiovascular diseases, diabetes mellitus, autoimmune (rheumatoid arthritis), neurodegenerative disorders (Alzheimer's and Parkinson's disease), have also been investigated. However, the findings remain limited or inconclusive. Thus, additional high-quality clinical studies are necessary to confirm this association.
Clinical Significance:
This review is important as it identifies the potential relationship between denture-wearing and systemic diseases, particularly respiratory diseases. It sheds light on the potential systemic risks or benefits associated with denture-wearing.
More Related Videos
Related Concept Videos
01:15Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
01:26Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
01:11Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
01:21Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...