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Association between removable denture-wearing and systemic diseases: A scoping review
Tong Wah Lim1, Karuna Julia Ka Wing Li1, Jingyu Wang1
1Division of Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR.
Journal of Dentistry
|July 16, 2025
Summary
Removable denture-wearing may be linked to systemic diseases, especially respiratory conditions. Further research is needed to confirm these associations and understand potential health impacts.
Area of Science:
- Oral Health and Systemic Diseases
- Clinical Evidence Synthesis
Background:
- The relationship between removable denture use and systemic health remains incompletely understood.
- Investigating potential links between oral prosthetics and broader physiological conditions is crucial for public health.
Purpose of the Study:
- To conduct a scoping review of clinical studies examining the association between removable denture-wearing and systemic diseases.
- To identify potential mechanisms linking denture use to systemic health outcomes.
Main Methods:
- A comprehensive electronic search was performed across five major databases and one register.
- 30 full-text studies were included after rigorous eligibility screening.
- Data were systematically extracted and summarized to synthesize findings.
Main Results:
- A potential association between removable denture-wearing and respiratory diseases was identified.
- Investigated systemic diseases included cardiovascular, diabetes mellitus, autoimmune, and neurodegenerative disorders.
- Evidence for these associations was found to be limited or inconclusive.
Conclusions:
- Removable denture-wearing is associated with five categories of systemic diseases, notably respiratory conditions.
- Further high-quality clinical research is essential to validate these associations.
- This review highlights potential systemic risks and benefits of denture use.
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