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Updated: Sep 15, 2025

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Renal denervation for managing hypertension: Key elements in selecting and referring patients
Michael A Weber1, Eric A Secemsky2, Anna Krawisz2
1Division of Cardiovascular Medicine, SUNY Downstate Medical Center, Brooklyn, NY, United States of America.
Renal denervation (RDN) offers a new treatment for uncontrolled high blood pressure. This paper outlines models for integrating RDN referral pathways into healthcare systems to improve patient access and outcomes.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Nephrology
Background:
- Resistant hypertension affects many patients despite lifestyle changes and medication.
- Renal denervation (RDN) is an approved therapy for difficult-to-control hypertension.
- Effective patient referral pathways are crucial for RDN accessibility.
Purpose of the Study:
- To explore program models for integrating RDN into clinical practice.
- To discuss strategies for creating accessible patient referral pathways for RDN.
- To optimize the application of RDN for improved hypertension management.
Main Methods:
- Review of current healthcare system structures for hypertension management.
- Analysis of decentralized and centralized RDN program models.
- Consideration of patient selection criteria and team-based care approaches.
Main Results:
- Checklists can facilitate patient selection in community practices.
- Centralized and decentralized models offer different integration approaches.
- Multidisciplinary teams are key for successful patient selection and RDN program management.
Conclusions:
- Implementing structured RDN referral pathways can enhance patient access to this therapy.
- Careful patient selection by expert teams is vital for RDN efficacy.
- Optimized RDN integration can improve hypertension control and reduce cardiovascular risk.
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