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Updated: Sep 15, 2025

Transient Transduction of the Strobilated Forms of Echinococcus granulosus
Published on: September 16, 2022
Unlocking the potential of miRNAs in cystic echinococcosis
Paola Pepe1, Elena Ciccone1, Nunzio Antonio Cacciola1
1Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via F. Delpino 1, Naples, 80137, Italy.
Abstract:
This review explores the potential of microRNAs (miRNAs) as diagnostic and therapeutic targets to enhance control programs for cystic echinococcosis (CE), a zoonotic parasitic disease posing significant threats to global human and animal health. Scientific evidence has demonstrated that Echinococcus-derived miRNAs are present in the biofluids of infected hosts, underscoring their potential for CE diagnosis. Additionally, specific miRNAs from Echinococcus granulosus sensu lato have been shown to influence host-parasite interactions, making them promising therapeutic targets for CE. In conclusion, further investigation into the role of miRNAs in CE could lead to significant breakthroughs in the fight against this neglected disease.

