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Mohs surgery for periocular basal cell carcinomas.
Summary
Mohs surgery offers high cure rates for periocular basal cell carcinomas. However, medial canthal lesions, especially those previously treated with radiation, show higher recurrence rates, indicating a need for careful management.
Area of Science:
- Dermatology
- Surgical Oncology
Background:
- Basal cell carcinoma (BCC) is the most common type of skin cancer.
- Periocular BCC presents unique challenges due to anatomical complexity and proximity to vital structures.
Purpose of the Study:
- To evaluate the efficacy of Mohs surgery for periocular basal cell carcinomas.
- To identify risk factors for recurrence in treated periocular BCCs.
Main Methods:
- Retrospective analysis of 631 periocular basal cell carcinoma cases treated with Mohs surgery.
- Comparison of cure rates and recurrence patterns based on lesion location and prior treatment history.
Main Results:
- Overall cure rates were 98.1% for primary and 93.6% for previously treated lesions.
- Recurrence rates were significantly higher for medial canthal lesions (9.5%) compared to other periocular sites (4.5%) in previously treated cases.
- Medial canthal lesions previously treated with radiation had a threefold increased risk of recurrence.
Conclusions:
- Mohs surgery is highly effective for primary periocular basal cell carcinomas, including those in the medial canthus.
- Previous radiation therapy is a significant risk factor for recurrence in medial canthal BCCs treated with Mohs surgery.
- Careful consideration of treatment history is crucial for managing periocular basal cell carcinomas, particularly in the medial canthus.