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Aggregation-Driven Fluorescence: Decoding Cooperative Artificial Motors Enable Bimodal Emission in Semi-Solid
Sudeshna Kalita1,2, Anup Singhania1,2, Amit Kumar Pathak1,2
1Natural Product Chemistry Group, Chemical Sciences & Technology Division, CSIR-North East Institute of Science & Technology, Jorhat, Assam, India.
Macromolecular Rapid Communications
|July 16, 2025
Summary
Artificial rotary motors integrated into chitosan matrices exhibit unique fluorescence changes. This study explores their cooperative working principles for advanced biohybrid systems and adaptive synthetic materials.
Area of Science:
- Materials Science
- Chemical Engineering
- Biotechnology
Background:
- Artificial rotary motors are crucial for biohybrid systems, enabling functions like ion transport.
- Integrating these motors into adaptive systems presents significant challenges.
Purpose of the Study:
- To investigate the cooperative working principle of a double ratchet motor (DRM) in a semi-solid chitosan matrix.
- To understand the mechanisms behind DRM aggregation-induced fluorescence emission.
Main Methods:
- Studied a double ratchet motor (DRM) composed of Brownian and power stroke rotors coupled to a -C≡C- stator.
- Explored DRM behavior within a chitosan matrix and fabricated DRM-embedded chitosan hybrid films.
- Analyzed thermally activated metastable rotational states and binary solvent-induced clustering.
Main Results:
- DRMs in chitosan matrices showed thermally activated metastable rotational states.
- These states led to aggregation-induced fluorescence emission with both blue and red shifts.
- DRM aggregation was attributed to binary solvent-induced clustering.
Conclusions:
- Findings provide molecular insights into motor-driven fluorescence modulation.
- Advances the potential of artificial motors in biohybrid materials.
- Paves the way for integration into biochemical reaction networks and adaptive synthetic systems.
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