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Updated: Sep 15, 2025

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Heart transplantation in congenital heart disease: long-term outcomes and complications
1Mayo Clinic, Rochester, Minnesota, USA.
Insights
Outcomes for heart transplantation in patients with congenital heart disease are improving. Further research is needed to optimize results and ensure equitable access to heart transplants for these patients.
Area of Science:
- Cardiology
- Transplantation Medicine
- Congenital Heart Disease
Background:
- Congenital heart disease (CHD) patient populations are growing in number, complexity, and disease severity.
- Heart transplantation referrals for CHD patients are increasing.
Purpose of the Study:
- To examine short-term and long-term outcomes data for heart transplantation in CHD patients.
- To highlight recent advances in transplantation for complex CHD cases.
- To ensure equitable access to heart transplantation for CHD patients.
Main Methods:
- Review of short-term and long-term outcomes data.
- Special attention to single-ventricle patients.
- Inclusion of multiorgan transplantation data, including combined heart and liver transplantation.
Main Results:
- Analysis of outcomes data for heart transplantation in CHD patients.
- Examination of outcomes in single-ventricle patients.
- Review of advances in combined heart and liver transplantation.
Conclusions:
- Optimizing heart transplantation outcomes in CHD patients is crucial due to limited organ supply.
- Ensuring equity in heart transplantation for CHD patients compared to non-CHD patients is necessary.
Purpose Of Review:
Heart transplantation referrals in congenital heart disease patients are increasing as this population grows in number, complexity, and disease severity.
Recent Findings:
We examine short-term and long-term outcomes data with special attention to single-ventricle patients and multiorgan transplantation, including recent advances in combined heart and liver transplantation.
Summary:
Given the limited supply of available organs for transplantation, it is necessary to examine heart transplantation outcomes in congenital heart disease patients to better optimize outcomes and ensure equity with noncongenital heart disease patients.
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