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Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria
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Spectral analysis for base composition of DNA undergoing melting

R D Blake, T G Hydorn

    Journal of Biochemical and Biophysical Methods
    |November 1, 1985
    PubMed
    Summary

    This study presents a microcomputer-controlled spectrophotometer for DNA base composition analysis. It achieves high precision in determining adenine-thymine (A-T) and guanine-cytosine (G-C) content from melting curves.

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