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Epidemiological and Surgical Insights into Inverted Papillomas: A Tertiary Center Experience
Rezarta Taga Senirli1, Özer Erdem Gür2
1Otolaryngology - Head and Neck Surgery, Antalya Training and Research Hospital, Antalya, TUR.
Cureus
|July 17, 2025
Summary
Sinonasal inverted papillomas (IPs) are locally aggressive tumors, predominantly affecting males. Endoscopic surgery offers good outcomes for these sinonasal tumors, but long-term monitoring is essential due to malignant transformation risks.
Area of Science:
- Otolaryngology
- Neurosurgery
- Oncology
Background:
- Sinonasal inverted papillomas (IPs) are benign tumors with a propensity for local invasion and recurrence.
- These tumors can exhibit malignant transformation, necessitating thorough evaluation and management.
Purpose of the Study:
- To characterize the epidemiology, clinical presentation, diagnostic methods, and surgical outcomes of sinonasal IPs.
- To compare findings with existing literature and assess the efficacy of endoscopic resection.
Main Methods:
- Retrospective review of 25 patients with sinonasal IPs treated between 2015 and 2021.
- Analysis of demographic data, symptoms, imaging, surgical procedures, and postoperative outcomes.
Main Results:
- A strong male predominance (23/25) was observed, with a mean age of 54.7 years.
- Nasal obstruction was the most frequent symptom; tumors often originated from the maxillary sinus.
- Endoscopic resection was successful in most cases, with a low revision rate (16%); two cases showed malignant transformation.
Conclusions:
- Sinonasal IPs, despite being benign, behave aggressively and pose a risk of malignant change.
- Endoscopic surgery provides favorable outcomes for IPs, emphasizing the need for long-term patient surveillance.
