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Related Concept Videos

Vaccinations01:51

Vaccinations

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Overview
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Factors Affecting Illness01:18

Factors Affecting Illness

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When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
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Immunological Memory01:23

Immunological Memory

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Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
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Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

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When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
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Current Trends in Nursing I01:28

Current Trends in Nursing I

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Current trends in nursing include:
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  1. Home
  2. Research Domains
  3. Language, Communication And Culture
  4. Cultural Studies
  5. Postcolonial Studies
  6. Why Do Older Adults Hesitate To Get The Flu Vaccine? A Cross-sectional Study On Vaccine Hesitancy In The Post-covid-19 Era

Why do older adults hesitate to get the flu vaccine? A cross-sectional study on vaccine hesitancy in the post-COVID-19 era

Xinyue Wang1, Sanmei Wen2, Jiaqian Wu1

  • 1Xuhui District Center for Disease Control and Prevention, Shanghai, China.

Frontiers in Public Health
|July 17, 2025

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View abstract on PubMed

Summary
This summary is machine-generated.

Influenza vaccine hesitancy is high in Shanghai older adults due to low confidence and complacency. Addressing these factors and improving vaccine literacy is crucial for increasing vaccination rates.

Area of Science:

  • Public Health
  • Epidemiology
  • Gerontology

Background:

  • Influenza vaccination is critical for older adults, yet hesitancy remains a significant public health challenge.
  • Understanding the multifaceted determinants of vaccine hesitancy (VH) is essential for targeted interventions.

Purpose of the Study:

  • To investigate the drivers of influenza VH among older adults in Shanghai, China.
  • To examine the roles of the 3Cs model (confidence, complacency, convenience) and vaccine literacy (VL).
  • To explore the influence of COVID-19 vaccine hesitancy on influenza vaccine attitudes.

Main Methods:

  • A community-based cross-sectional study was conducted in Shanghai involving 1,300 adults aged ≥60 years.
  • Stratified random sampling was used for participant recruitment.
Keywords:
3Cs modelinfluenzaolder adultvaccination hesitancy

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  • Multinomial logistic regression and structural equation modeling (SEM) were employed to identify predictors and interrelationships of VH.
  • Main Results:

    • A high prevalence of influenza VH (85.2%) was observed, with 16.2% complete refusal.
    • Key predictors included distrust in efficacy, low perceived severity, overreliance on non-pharmaceutical interventions (NPIs), and influenza-specific medication.
    • Limited communication with health workers and low family support amplified refusal, while higher vaccine knowledge reduced hesitancy, but critical VL showed paradoxical effects.

    Conclusions:

    • Deficits in vaccine confidence and complacency regarding influenza severity are primary drivers of VH in older adults.
    • COVID-19 vaccine skepticism and complex VL aspects exacerbate influenza VH.
    • System-level interventions should include proactive counseling, family engagement, and tailored, misinformation-resilient VL programs.
    vaccine literacy