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Multidisciplinary Approach to Obesity Management: A Case Report
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How do patients choose between obesity medications: A thematic analysis

Alvin Mondoh1,2,3, Hilary Craig1,2, Michael Crotty3

  • 1Diabetes Complications Research Centre, Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Dublin 4, Ireland.

Obesity Pillars
|July 17, 2025
PubMed
Abstract

Insights

Patient choices for obesity medications are influenced by effectiveness, safety, and practicality. Clear information and support from healthcare providers are crucial for successful obesity management and treatment adherence.

Area of Science:

  • Medical Research
  • Public Health
  • Pharmacology

Background:

  • Obesity is a growing global health concern linked to severe conditions like type 2 diabetes, cardiovascular diseases, and cancer.
  • While obesity medications can manage the condition, patient selection criteria remain unclear.

Purpose of the Study:

  • To investigate how patients choose between different obesity medications.
  • To identify key factors influencing patient decision-making in pharmacotherapy for obesity.

Main Methods:

  • A qualitative thematic analysis was performed.
  • Fifteen treatment-naive adults with obesity (BMI ≥27 kg/m²) and weight-related complications participated.

Main Results:

  • Five major themes emerged: medication effectiveness, decision-making information, safety, practicality, and individual/community support.
  • Concerns regarding side effects and long-term risks were significant barriers to initiating or adhering to obesity pharmacotherapy.

Conclusions:

  • Patient preferences for obesity medications are shaped by efficacy, safety, and healthcare provider information, especially when medications are accessible and free.
  • Enhancing patient adherence and outcomes requires healthcare providers to offer clear, comprehensive information and robust support systems.
Keywords:
EffectivenessObesityObesity medicationSafetyType 2 diabetesWeight loss

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