Related Experiment Video

Updated: Sep 15, 2025

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
04:32

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Published on: June 28, 2018

12.0K

Predictors of ventilator-associated pneumonia in intubated pediatric trauma patients

Fnu Avinash1, Jeffry Nahmias1, Negaar Aryan1

  • 1Department of Surgery, Division of Division of Trauma, Burns and Surgical Critical Care, University of California, Irvine Medical Center, 3800 Chapman Ave, Suite 6200, Orange, Irvine, CA, 92868-3298, USA.

Pediatric Surgery International
|July 17, 2025
PubMed

Insights

Unplanned reintubation, traumatic brain injury (TBI), and severe thoracic injuries are key risk factors for ventilator-associated pneumonia (VAP) in pediatric trauma patients. Identifying these factors can guide interventions to reduce VAP incidence and improve outcomes.

Area of Science:

  • Trauma Surgery
  • Critical Care Medicine
  • Pediatric Intensive Care

Background:

  • Ventilator-associated pneumonia (VAP) is a significant complication in intubated pediatric trauma patients (PTPs).
  • VAP increases mortality and healthcare costs, necessitating identification of associated risk factors.
  • Early risk factor identification can inform targeted interventions.

Purpose of the Study:

  • To identify risk factors associated with VAP in intubated pediatric trauma patients.
  • To analyze data from the Trauma Quality Improvement Program database (2017-2021).
  • To compare outcomes between PTPs with and without VAP.

Main Methods:

  • Retrospective analysis of the 2017-2021 Trauma Quality Improvement Program database.
  • Inclusion of all intubated pediatric trauma patients.
  • Bivariate and multivariable logistic regression analyses to identify risk factors.

Main Results:

  • Out of 38,593 intubated PTPs, 819 (2.1%) developed VAP.
  • VAP cohort showed higher injury severity scores, traumatic brain injury (TBI), rib fractures, and lung injuries.
  • Independent risk factors for VAP included unplanned reintubation (OR 2.51), TBI (OR 1.96), and severe thoracic injury (OR 1.27).

Conclusions:

  • Unplanned reintubation, TBI, and severe thoracic injuries are significant risk factors for VAP in intubated PTPs.
  • Findings underscore the need for strategies to minimize reintubation.
  • Optimizing ventilator management and pulmonary care for high-risk PTPs is crucial.
Abstract

Keywords:
Pediatric intensive carePediatric traumaPulmonary complicationVAPVentilator-associated pneumonia

More Related Videos

Guidelines for Elective Pediatric Fiberoptic Intubation11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

17.7K
Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS

Published on: April 7, 2021

3.5K

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
338
Endotracheal Intubation II: Nursing Management01:17

Endotracheal Intubation II: Nursing Management

Endotracheal intubation is a critical procedure that can be lifesaving for many patients with respiratory distress or failure. The role of nursing in managing endotracheal tubes is pivotal, as it involves pre-intubation preparation, assisting during the procedure, and post-extubation care.
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
1.3K
Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
257
Factors Affecting Pulmonary Ventilation01:19

Factors Affecting Pulmonary Ventilation

Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.6K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
450
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
980