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Updated: Sep 15, 2025

Hydrophobic Salt-modified Nafion for Enzyme Immobilization and Stabilization
Published on: July 11, 2012
MOF-based hybrid electrodes for multi-enzyme cascade reactions with stabilized mediator immobilization
Kotoko Ariga1, Muhammad Rezki1, Kayo Suzuki-Nagata2
1Graduate School of Pure and Applied Science, University of Tsukuba, 1-1-1, Tennodai, Tsukuba 305-8573, Japan.
Abstract:
ZIF67-NQS/CNT hybrid electrodes enabling stable mediator immobilization and efficient multi-enzyme cascade reactions exhibited enhanced current output attributed to the cascade effect. Notably, the pyruvate byproduct inhibited lactate oxidase activity, while its elimination via pyruvate decarboxylase significantly improved the current response. This strategy offers both mechanistic insights and practical advantages.
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