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Laboratory Characteristics of Lymphoplasmacytic Lymphoma with Plasma Cells Containing “Diamond-Shaped” Inclusions

Yu Ma1, Guochang Zhang1, Yingchun Zheng2

  • 1Anshan Central Hospital, Clinic of Clinical Laboratory, Anshan, P.R. China

Turkish Journal of Haematology : Official Journal of Turkish Society of Haematology
|July 17, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Lymphoplasmacytic lymphomaInclusionsPlasma cellsLaboratory diagnosis

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In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops resemble the...