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Updated: Sep 15, 2025

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat
Published on: August 30, 2020
Novel Mechanism for Preserving Stump Length During Revision of Endoprosthetic Limb Salvage: A Case Report
Alan Li1, Michael Russell2, Christopher D Hamad2
1David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
Case:
An 18-year-old woman with osteosarcoma of the left distal femur underwent resection and limb-salvage surgery with compressive osseointegration endoprosthetic reconstruction and experienced tumor recurrence 1 year after index surgery. A transfemoral amputation was performed preserving the existing compressive osseointegration device, and limb lengthening was achieved using intercalary and distal femoral segments. 3.5 years after amputation and lengthening, the implant remains well integrated and the patient is ambulatory.
Conclusion:
Compressive osseointegration with distal femoral endoprosthesis is a viable option for adding length and lever arm mechanics in patients with short stump above knee amputations.
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