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The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
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Concomitant functional gallbladder disorder and left-sided gallbladder: A case report.

Jing-Rui Wu1, Chang-Cheng Wang2, Bo-Yang Li2

  • 1Department of Surgery, The Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, Shanxi Province, China.

World Journal of Gastrointestinal Endoscopy
|July 18, 2025
PubMed
Summary
This summary is machine-generated.

This report details the first case of functional gallbladder disorder (FGBD) in a patient with a left-sided gallbladder. Surgical removal of the ectopic gallbladder resolved the patient's symptoms, highlighting diagnostic and surgical considerations.

Keywords:
Abdominal painCase reportEctopic gallbladderFunctional gallbladder disorderGallbladder anatomical variationLaparoscopic cholecystectomy

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Area of Science:

  • Gastroenterology and Hepatobiliary Surgery
  • Diagnostic Imaging and Interventional Radiology

Background:

  • Ectopic gallbladder, a rare anomaly (0.1%-0.7%), typically occurs without situs inversus totalis.
  • Functional gallbladder disorder (FGBD) presents with biliary pain, normal imaging, and impaired gallbladder contraction.
  • Concomitant FGBD and left-sided gallbladder represent a unique clinical challenge with no prior reported cases.

Observation:

  • A 73-year-old woman presented with a 20-year history of epigastric pain.
  • Diagnosis of left-sided gallbladder and FGBD was established via imaging and functional assessment.
  • Laparoscopic cholecystectomy confirmed an ectopic gallbladder in the left liver lobe.

Findings:

  • Postoperative pathology showed no abnormalities.
  • The patient experienced complete symptom resolution three months after surgery.
  • This case represents the first documented instance of FGBD co-occurring with a left-sided gallbladder.

Implications:

  • Preoperative imaging (MRI/CT) is essential for identifying gallbladder anatomical variations.
  • Laparoscopic cholecystectomy is a viable treatment option but necessitates meticulous surgical planning.
  • This case underscores the importance of considering rare anatomical variations in diagnosing and managing gallbladder disorders.