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Comparison of Outcomes Between Primary Laryngotracheal Reconstruction and Partial Cricotracheal Resection in Moderate
Bigyan Raj Gyawali1, Heempali Dutta1, Anuj Devkota1
1Department of ENT and Head Neck Surgery Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital Kathmandu Nepal.
Insights
Laryngotracheal reconstruction (LTR) and partial cricotracheal resection (PCTR) offer comparable success rates for pediatric subglottic stenosis. Partial cricotracheal resection may provide better functional outcomes, but more research is needed.
Area of Science:
- Pediatric Otolaryngology
- Pediatric Airway Surgery
- Respiratory Medicine
Background:
- Moderate-grade pediatric subglottic stenosis (severe Grade II and III) requires surgical intervention.
- Laryngotracheal reconstruction (LTR) and partial cricotracheal resection (PCTR) are common surgical techniques.
- A clear consensus on the optimal surgical approach is lacking.
Purpose of the Study:
- To systematically compare the outcomes of primary laryngotracheal reconstruction (LTR) versus partial cricotracheal resection (PCTR).
- To evaluate surgical success in managing moderate-grade pediatric subglottic stenosis.
Main Methods:
- Systematic literature search of PubMed, Embase, and Scopus adhering to PRISMA guidelines.
- Inclusion of studies on pediatric patients (<18 years) with severe Grade II or III subglottic stenosis.
- Primary outcome: successful extubation or decannulation; statistical analysis using STATA.
Main Results:
- 24 studies included 193 patients (LTR) and 88 patients (PCTR).
- Successful decannulation rates: 83.93% (LTR) vs. 96.59% (PCTR), not statistically significant (p=0.47).
- PCTR showed slightly better voice/swallowing outcomes; LTR had higher restenosis/revision rates.
Conclusions:
- Both LTR and PCTR are effective for moderate-grade pediatric subglottic stenosis with similar decannulation success.
- PCTR may offer advantages in functional outcomes.
- Further research with standardized reporting is needed to determine the optimal surgical approach.
Objective:
This systematic review and meta-analysis compare the outcomes of primary laryngotracheal reconstruction (LTR) and partial cricotracheal resection (PCTR) in managing moderate-grade pediatric subglottic stenosis (severe Grade II and Grade III). While both surgical approaches are widely used, no clear consensus exists on the superior technique.
Methods:
A systematic literature search was conducted across PubMed, Embase, and Scopus following PRISMA guidelines. Studies reporting outcomes of LTR and PCTR in pediatric patients (< 18 years) with severe Grade II (> 60%) or Grade III subglottic stenosis were included. The primary outcome was successful extubation or decannulation. Statistical analysis, including pooled prevalence estimates and heterogeneity assessment, was performed using STATA software.
Results:
A total of 24 studies were included, comprising 193 patients in the LTR group and 88 in the PCTR group. Successful decannulation was achieved in 83.93% of LTR cases and 96.59% of PCTR cases. However, the difference was not statistically significant (p = 0.47). Failed decannulation in both groups was associated with factors such as neurological disorders, severe airway scarring, and coexisting airway anomalies. PCTR demonstrated slightly better functional outcomes in voice and swallowing, whereas LTR was associated with a higher risk of restenosis and revision surgeries.
Conclusion:
Both LTR and PCTR are viable options for moderate-grade pediatric subglottic stenosis, with comparable decannulation success rates. PCTR may offer advantages in functional outcomes, but further research with standardized reporting is necessary to establish an optimal surgical approach.
Level Of Evidence:
II.
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