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Related Experiment Videos

Esophageal intramural pseudodiverticulosis.

J Fromkes, F B Thomas, H Mekhjian

    The American Journal of Digestive Diseases
    |August 1, 1977
    PubMed
    Summary

    Esophageal intramural pseudodiverticulosis (EIP) is an inflammatory condition causing dilated esophageal glands. This review covers its diagnosis, symptoms like dysphagia, and frequent complications such as strictures and motility issues.

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    Area of Science:

    • Gastroenterology
    • Pathology

    Background:

    • Esophageal intramural pseudodiverticulosis (EIP) is a rare condition.
    • Its etiology remains largely unknown, though it is characterized as an inflammatory process.

    Observation:

    • EIP presents radiographically with characteristic collar-button-shaped outpouchings.
    • The condition typically affects individuals in their sixth and seventh decades, but can occur at any age.
    • Dysphagia is a common symptom, though not universally present.

    Findings:

    • The radiographic appearance is attributed to the dilatation of the esophageal submucosal glandular ductal system.
    • Comorbidities include diabetes mellitus in approximately one-third of patients.
    • Esophageal strictures, esophagitis, and significant motility disturbances are frequently observed.

    Implications:

    • Early recognition of EIP is crucial for managing potential complications.
    • The association with Candida infestation necessitates thorough investigation in all EIP cases.
    • Understanding EIP's inflammatory nature may guide future therapeutic strategies.

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