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A global perspective on autoinducer-2-mediated cell communication in prokaryotes

Xiaozhen Liu1,2, Zhiyan Wei1,3, Mingming Yang3

  • 1Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Science, Northwest A&F University, Yangling, Shaanxi 712100, China.

Iscience
|July 18, 2025
PubMed
Summary

Prokaryotes use quorum sensing (QS) for communication. This study maps microbial cell-cell communication across 15,297 genomes, revealing widespread LsrB receptor roles in gene regulation and biofilm formation.

Keywords:
Biological sciencesMicrobiologyMolecular biology

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