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Updated: Sep 15, 2025

CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells
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LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Diana Corallo1, Sara Menegazzo1,2, Marcella Pantile1

  • 1Laboratory of Target Discovery and Biology of Neuroblastoma, Pediatric Hematology, Oncology and Hematopoietic Cell&Gene Therapy Research Area, Institute of Pediatric Research, Fondazione Città della Speranza, Padua, 35127, Italy.

Advanced Biology
|July 18, 2025
PubMed
Summary

LIN28B overexpression promotes neuroblastoma metastasis by enhancing cell adhesion, migration, and angiogenesis. This protein hub drives aggressive phenotypes by influencing endothelial cells and extracellular matrix interactions.

Keywords:
LIN28Bangiogenesismigrationneuroblastomapre‐metastatic niche

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