Impact of Acute In-Hospital Postburn Pruritus on Quality of Life: A Cross-Sectional Study

Itching following a burn injury is a frequent complication that significantly affects patients' well-being. Despite its prevalence, the acute effects of itching during hospitalization and its correlation with specific burn characteristics remain under-researched, particularly in non-Western populations. In 2021, we carried out a cross-sectional study involving 268 adult patients who were admitted for a minimum of 48 hours after burn injury. We collected data through interviews and medical records, focusing on demographics, burn severity-categorized by total body surface area, tissue damage depth, and specific anatomical locations-and itch parameters, which were evaluated using a patient-reported intensity scale (0-10), duration, and areas affected. We utilized the ItchyQoL questionnaire to measure long-term well-being and the impact of itching on physical, emotional, and functional quality of life. Analyses included parametric and nonparametric tests as well as multivariable regression to evaluate how characteristics of itch and burn severity influenced recovery and quality of life. Itchy patients exhibited more extensive skin damage, deeper injuries, and prolonged hospitalizations compared with those without itching. Increased itch intensity and duration were linked to lower ItchyQoL scores, signifying a greater detrimental effect on quality of life. In multivariable analysis, itch intensity was identified as the most significant predictor of diminished well-being. The severity and duration of itching during hospitalization notably impact recovery and long-term quality of life. Addressing severe itching early can reduce hospital stays and promote healing.