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Published on: August 8, 2019
Sleep Duration Transitions Among Children With Central Precocious Puberty Across Pubertal Development
Wen-Yu Lin1, Jia-Woei Hou2, Li Huang3
1Department of Family Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan.
Insights
Insufficient sleep and late bedtimes are linked to central precocious puberty (CPP) in girls. Maintaining adequate sleep and earlier bedtimes is recommended for girls before puberty onset.
Area of Science:
- Pediatric Endocrinology
- Sleep Medicine
- Child Development
Background:
- Central precocious puberty (CPP) is a condition where puberty begins unusually early.
- The influence of sleep patterns on CPP development is not well understood.
- Longitudinal sleep data in children with CPP is lacking.
Purpose of the Study:
- To investigate sleep parameters associated with CPP in children.
- To examine sleep duration changes before and after puberty onset.
- To determine if insufficient sleep or later bedtimes are risk factors for CPP.
Main Methods:
- Analysis of data from 2238 children in the Taiwan Pubertal Longitudinal Study.
- Longitudinal assessment of sleep parameters and pubertal staging every 3 months.
- Identification of critical sleep parameters linked to CPP onset.
Main Results:
- CPP was associated with age, gender, fat percentage, and moderate physical activity.
- Girls with CPP reported significantly more insufficient sleep and later bedtimes.
- No significant association between sleep parameters and CPP risk was found in boys.
Conclusions:
- Insufficient sleep and late bedtimes may be key factors in CPP development.
- Recommendations include ensuring sufficient sleep and earlier bedtimes for girls, especially pre-puberty.
- These modifiable sleep behaviors may help mitigate CPP risk.
Purpose:
The relationships between insufficient sleep, later bedtime, and central precocious puberty (CPP) among children remain unclear. No study has ever longitudinally followed the sleep parameters among children with CPP throughout pubertal growth. This study aimed to investigate the independent sleep parameters associated with CPP in children and examine the changes in sleep duration that occur before and after puberty onset.
Methods:
Data from 2238 children in the Taiwan Pubertal Longitudinal Study were analyzed to identify critical sleep parameters associated with CPP. In addition, longitudinal measures of sleep parameters and pubertal staging were assessed every 3 months following enrollment to examine the relationship between crucial puberty onset period and sleep duration transitions.
Results:
CPP status was associated with age (p < .001), gender (p < .001), fat percentage (p < .001), and moderate physical activity (p = .007). Girls with CPP were more likely to report insufficient sleep (odds ratio, 1.329; 95% confidence interval, 1.061-1.664; p = .013) and late bedtime (odds ratio, 1.576; 95% confidence interval, 1.144-2.171; p = .005) compared to girls without CPP. However, none of the sleep-related parameters were significantly associated with an increased risk of CPP in boys.
Discussion:
Insufficient sleep and late bedtime may be critical determinants of CPP. Due to their modifiable nature, we recommend that girls maintain sufficient sleep duration and adhere to earlier sleep times, particularly before puberty.
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