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Initial experience of mitral valve repair using the Physio Flex Annuloplasty Ring

Kosaku Nishigawa1, Shuhei Kawamoto2, Kazuki Morooka2

  • 1Department of Cardiovascular Surgery, IMS Katsushika Heart Center, 3-30-1 Horikiri, Katsushika, Tokyo, 124-0006, Japan. nippie550102@yahoo.co.jp.

General Thoracic and Cardiovascular Surgery
|July 18, 2025
PubMed
Abstract

Insights

Mitral valve repair using the Physio Flex Annuloplasty Ring effectively controlled mitral regurgitation in 185 patients. Early outcomes were satisfactory, with a low rate of residual regurgitation and acceptable incidence of functional mitral stenosis.

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Surgery
  • Medical Devices

Background:

  • Mitral regurgitation (MR) is a significant valvular heart disease.
  • Effective mitral valve (MV) repair is crucial for improving patient outcomes.
  • Annuloplasty rings are commonly used to support MV repair.

Purpose of the Study:

  • To evaluate early clinical and echocardiographic outcomes of mitral valve repair using the Physio Flex Annuloplasty Ring.
  • To assess the efficacy of the Physio Flex Annuloplasty Ring in various etiologies of mitral regurgitation.

Main Methods:

  • Retrospective analysis of 185 patients undergoing MV repair with Physio Flex Annuloplasty Ring (July 2020 - October 2024).
  • Patients had degenerative or functional MR, with severe or moderate regurgitation.
  • Surgical techniques included artificial chordal reconstruction, leaflet resection, folding plasty, and ring annuloplasty alone.

Main Results:

  • The operative mortality rate was 2.2%.
  • Postoperative no/trivial or mild MR was observed in 97.3% of patients.
  • Significant reductions in left ventricular dimensions and right ventricular systolic pressure were noted (P < 0.001).
  • Functional mitral stenosis occurred in 13 patients.

Conclusions:

  • Mitral valve repair with the Physio Flex Annuloplasty Ring demonstrates effective MR control.
  • Satisfactory early clinical and echocardiographic outcomes were achieved.
  • The incidence of functional mitral stenosis is acceptable.
Keywords:
Functional mitral stenosisMitral annuloplastyMitral valve repair

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