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Regression Toward the Mean01:52

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Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
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Well-Being in Psoriasis: Weighting its Components Using Best-worst Scaling Methodology.

Esteban Daudén1, Isabel Belinchón2, Elena Colominas-González3

  • 1Department of Dermatology, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa (IIS-IP), Diego de León, 62, 28006, Madrid, Spain. estebandauden@gmail.com.

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|July 18, 2025
PubMed
Summary

Patients and healthcare professionals differ on key well-being factors for psoriasis. Pain and stress are paramount for patients, while mood disorders and pain are crucial for HCPs, impacting psoriasis care strategies.

Keywords:
Best-worst scalingPsoriasisQuality of lifeWell-being

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Area of Science:

  • Dermatology
  • Psychology
  • Health Services Research

Background:

  • The Inpsight Project (2021) defined well-being in psoriasis patients holistically.
  • Well-being encompasses emotional balance, health, disease control, social relations, and care satisfaction.
  • The relative importance of these well-being components requires further elucidation.

Purpose of the Study:

  • To determine the relative weight of well-being components for psoriasis patients in Spain.
  • To compare patient and healthcare professional (HCP) perspectives on well-being priorities.

Main Methods:

  • Observational, descriptive, cross-sectional study in Spain.
  • Best-Worst Scaling (BWS) methodology employed.
  • Two questionnaires for patients (33 items) and HCPs (18 items) assessing 20 well-being components.

Main Results:

  • Patients prioritized pain (100.00), stress (98.74), treatment satisfaction (92.21), itching (72.05), and functional lesions (69.09).
  • HCPs prioritized mood disorders (100.00), pain (69.39), functional lesions (49.34), self-esteem (49.24), and stigmatization (45.22).

Conclusions:

  • Significant discrepancies exist between patient and HCP perceptions of well-being components in psoriasis.
  • Understanding these differing perspectives is vital for optimizing psoriasis patient care.
  • Further research should explore the cumulative impact of psoriasis on patient well-being.