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Updated: Sep 14, 2025

Author Spotlight: Controlled Human Exposure Model for Tick Research and Lyme Disease Studies
Published on: December 1, 2023
Lyme disease vaccine acceptability among healthcare providers - United States, 2018 and 2022
Taylor D Bostic1, Sarah A Hook2, Grace E Marx2
1Division of Vector-borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA; Oak Ridge Institute for Science and Education, Centers for Disease Control and Prevention Fellowship Program, Oak Ridge, TN, USA.
Background:
A Lyme disease (LD) vaccine is expected to become available soon. We aimed to understand recent trends in healthcare provider (HCP) willingness to recommend LD vaccination.
Methods:
Cross-sectional surveys among HCPs were conducted in 2018 and 2022. We compared willingness to recommend LD vaccination by survey year and provider characteristics.
Results:
Among 3005 HCPs, 70.5 % reported willingness to recommend LD vaccination. This proportion was lower in 2022 than in 2018 (68 % vs 73 %; p < 0.01) and did not differ significantly by provider medical specialty. More HCPs in states with high LD incidence were willing to recommend the vaccine compared to HCPs in neighboring or low-incidence states (p < 0.01). Vaccine safety was the most frequently reported consideration for recommending LD vaccination (73 %).
Conclusions:
HCP willingness to recommend LD vaccination decreased from 2018 to 2022. Vaccination education tailored to HCPs that address vaccine safety will be critical for a successful LD vaccination program.
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