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Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
Published on: March 20, 2020
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TNBC's compass: Navigating prognosis with a cellular map
Yi-Fan Zhou1, Ding Ma1, Zhi-Ming Shao1
1Key Laboratory of Breast Cancer, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Cancer Cell
|July 18, 2025
Abstract
None:
In this issue of Cancer Cell, Meyer et al. use imaging mass cytometry and identify a stem-like basoluminal tumor cell linked to poor prognosis in triple-negative breast cancer (TNBC). They integrate this finding with T cell spatial architecture to establish a five-subtype classification for predicting prognosis and guiding therapy.
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