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Effects of regular exercise on blood rheology

Yi-Fan Wu¹, Jia-Lin Chen², Chien-Sung Tsai^3,4

¹Department of Biomedical Engineering, Ming-Chuan University, Taoyuan, Taiwan.

Scientific Reports

|July 18, 2025

Abstract

None:

Regular physical activity (RPA) promotes cardiovascular health but its effects on blood flow and rheology characteristics remain unclear. This study compared hemorheological parameters between healthy adults who regularly jogged (n = 35) and sedentary controls (n = 35). Participants in the RPA group showed significantly lower fibrinogen levels, C-reactive protein concentrations, blood viscosity, plasma viscosity, and red blood cell aggregation (all p < 0.05). They also had higher hematocrit and albumin concentrations. Blood viscosity decreased by around 30% (native) and 49% (hematocrit-adjusted) in active individuals. These findings suggest regular jogging improves blood flow, potentially protecting against cardiovascular diseases.

Keywords:

Blood rheology Exercise Red blood cell aggregation Viscosity

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