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Updated: Sep 14, 2025
Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation
Published on: January 7, 2021
Enhanced fetal MRI diagnosis of esophageal atresia using super-resolution slice-to-volume reconstruction
Delaney Loken1, Luis F Goncalves2,3,4, Mittun Patel2
1Creighton University, 3100 N Central Ave, Phoenix, AZ, 85012, United States. dbl73215@creighton.edu.
Background:
Prenatal diagnosis of esophageal atresia remains challenging, with indirect signs such as polyhydramnios, a small or absent stomach bubble, and a dilated upper esophageal pouch often inconsistently present. Only 10-40% of EA cases are diagnosed prenatally. Fetal MRI can overcome ultrasound limitations; however, constraints like motion can hinder evaluation of the esophagus.
Methods:
Super-resolution imaging with slice-to-volume reconstruction (SVR) is one approach that can improve image quality. This technique generates high-resolution 3D images from standard fetal MRI slices to enhance diagnostic accuracy.
Aim:
We present the application of super-resolution imaging with SVR to accurately diagnose EA and assess the presence or absence tracheoesophageal fistulas.
Conclusion:
This technique demonstrates significant potential for accurately delineating the relevant surgical anatomy, which can improve surgical planning.
