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Rheumatic Heart Disease III: Medical Management

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...

Rheumatic Heart Disease IV: Nursing Management

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AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...

Genome-wide Association Studies-GWAS

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Related Experiment Video

Updated: Sep 14, 2025

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

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Assisted Reproductive Technologies Outcomes in Women With Rheumatic Diseases: A Retrospective Cohort Study.

Elham Manouchehri¹, Fatemeh Jalalmarvi¹, Vahid Ghavami²

¹Department of Nursing and Midwifery, MMS.C, Islamic Azad University, Mashhad, Iran.

International Journal of Rheumatic Diseases

|July 19, 2025

Summary

Women with rheumatic diseases (RDs) undergoing assisted reproductive technologies (ART) face higher miscarriage and inadequate gestational weight gain risks. Personalized care is crucial for improved pregnancy outcomes in RDs.

Keywords:

assisted reproductive technology in vitro fertilization pregnancy pregnancy outcomes rheumatic diseases

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Published on: October 6, 2023

Area of Science:

Reproductive Medicine
Rheumatology
Obstetrics

Background:

Rheumatic diseases (RDs) and their treatments can impact pregnancy.
Assisted reproductive technologies (ART) offer fertility options for women with RDs.

Purpose of the Study:

To compare ART outcomes in women with and without RDs.

Main Methods:

Retrospective cohort study (August 2023-August 2024).
Analysis of ART outcomes from medical records of 194 women (62 with RDs, 132 without).
Statistical analysis included descriptive statistics, Mann-Whitney, Chi-squared/Fisher's exact tests, and confounder adjustment.

Main Results:

Women with RDs had a significantly higher risk of miscarriage (OR=5.27) and inadequate gestational weight gain (OR=2.25).
No significant differences in fetal/neonatal complications were observed between groups.
Larger studies may offer further insights into fetal/neonatal outcomes.

Conclusions:

Women with RDs undergoing ART require personalized, multidisciplinary care during pregnancy.
Management strategies should focus on mitigating risks like miscarriage and inadequate gestational weight gain.
Improved maternal and fetoneonatal outcomes are achievable with tailored care plans.